Faculty Positions in Immune Engineering and Cellular Therapies

Center for Cellular Therapies and Cancer Immunology (CCTCI)

Simmons Comprehensive Cancer Center

UT Southwestern Medical Center – Dallas, TX

The Center for Cellular Therapies and Cancer Immunology (CCTCI) at UT Southwestern Medical Center is recruiting tenure-track faculty at all academic ranks (Assistant, Associate, or Full Professor). We seek innovative scientists with expertise in immune engineering who are eager to develop transformative technologies and biologics to treat cancer.

About the Center

The CCTCI is a newly established, interdisciplinary center dedicated to accelerating the discovery and clinical translation of next-generation immunotherapies , including first-in-human Phase I trials . The Center leverages UT Southwestern’s world-class infrastructure in cellular manufacturing, genomics, and earlyphase clinical development to bridge bench and bedside.

Research Areas of Interest

We welcome applicants using cutting-edge tools to investigate and manipulate the immune system for therapeutic gain. Specific areas of interest include, but are not limited to:

• Machine learning applied to immunological challenges , such as modeling immune responses, antigen specificity, or cellular differentiation

• Protein engineering for immune modulation, including immune receptors, cytokines, and synthetic ligands

• Cellular engineering approaches, such as synthetic circuits, reprogramming, and in vivo cell targeting

• Genome engineering , including CRISPR-based systems, targeted epigenetic editing, and chromatin architecture manipulation for immunotherapy

Applicants working at the interface of computational, synthetic, and translational immunology are especially encouraged to apply.

Qualifications

• Ph.D., M.D., or equivalent degree in immunology, bioengineering, computational biology, or a related field

• A strong record of scientific innovation and productivity

• Demonstrated ability (or potential) to lead an independent, extramurally funded research program

• Commitment to interdisciplinary collaboration and mentorship

We are committed to building a diverse, equitable, and inclusive academic environment, and strongly encourage applications from individuals underrepresented in science and medicine.

Application Instructions

Interested candidates should submit the following materials:

• Cover letter

• Curriculum vitae

• 3-page research statement outlining past accomplishments and future directions

• Brief summary of up to three key publications (with links)

• Contact information for three referees

Review of applications will begin October 1, 2025 and continue until the positions are filled.

Apply online at

Tenure Track – Open Rank [Req#: 892019, Position#: 129683]

About UT Southwestern

UT Southwestern Medical Center is home to a vibrant and collaborative scientific community, including six Nobel Laureates , and over 80 members of the National Academies . We offer highly competitive startup packages, excellent benefits, and access to state-of-the-art core facilities and GMP infrastructure.

Learn more about UTSW employee benefits: